The complement system complements or enhances the immune system. These proteins cause a series of chain events that induce inflammation that helps antibodies clear infection. There are three pathways by which complement helps the immune system:
The classical, alternative, and lectin pathways.
The complement system and disease
The complement system is a perfectly normal part of the immune system but sometimes it goes haywire. Systemic lupus erythematous is a famous example. But there are also some rare diseases such as Degos/malignant atrophic papulosis.
Here is an excellent YouTube video explained the complement system presented by MEDSimplified
References
https://www.ncbi.nlm.nih.gov/books/NBK27100/