Injecting medication at home can seem daunting, but it doesn’t have to be. If your doctor has prescribed Yuflyma for your condition, such as rheumatoid arthritis, psoriasis, uveitis or Crohn’s disease, this comprehensive guide on how to inject Yuflyma at home will walk you through every step with clarity and confidence.
What is Yuflyma?
Yuflyma® (adalimumab-aaty), which you may be preparing to administer, is not just a standard therapeutic agent; it is, in fact, a biosimilar medication. As a biosimilar, it is highly similar to an existing biological medication, known as the ‘reference product’, which in this case is adalimumab, marketed under the brand name Humira®. Extensive comparison through analytical studies has shown that Yuflyma matches its reference in terms of potency, safety, and efficacy.
Despite the similarities, it is important to note that biosimilars are not labeled as “generic” versions of biologic medications because biologics are derived from living cells and are inherently complex, and it is impossible to create an exact copy. Rest assured, before approval, Yuflyma has gone through rigorous regulatory pathways to confirm that it is as safe and efficacious as the original biologic.
Preparing for Your First Self-Injection
Excited? Maybe a little nervous? Totally normal feelings when you’re about to take charge of your health in a hands-on way.
How to Inject Yuflyma at Home – Starting Steps
Clean Workspace: First thing’s first—find yourself a clean, well-lit area to prepare.
Hand Hygiene: Wash your hands with soap and water. It’s simple, but it’s one of the most effective ways to prevent infection.
Gather Supplies: Get your Yuflyma pre-filled syringe or pen, alcohol wipes, cotton balls, and a sharps container for disposal.
Storage Savvy: Remember, Yuflyma should be stored in the refrigerator. If it’s too cold to the touch, let it sit out for 30 minutes to reach room temperature. Never use a microwave or hot water to warm it.
Step-by-Step Injection Guide
Here’s the meat and potatoes of what you came for—how to inject Yuflyma at home:
Check It: Inspect your Yuflyma. It should be clear, and colorless to slightly yellow. If it’s cloudy or has particles, don’t use it.
Skin Selection: Choose your injection spot—either the front of your thighs or your belly, avoiding the waistline and staying two inches clear of the navel.
Clean Up: Swipe the selected area with an alcohol wipe and let it air dry.
Get Grip-Ready: Hold the pen firmly. Remove the needle cover when you’re set to go.
Pinch an Inch: With your free hand, gently pinch the skin around the injection site.
Needle in, Steady: Press the pen firmed onto your pinched skin at 90-degree angle.
Plunge with Confidence: Press the plunger down and steadily until all the medication is injected. It typically take 10 to 15 seconds.
Release and Withdraw: Let go of your skin. Pull the needle out while keeping it at the same angle it went in.
Praise and Press: Give yourself a little internal high-five for a job well done. Place a cotton ball over the site and apply pressure for a bit. If there’s bleeding, that’s okay. Just keep the pressure on a little longer.
Sensible Disposal: Don’t recap the needle. Pop it straight into the sharps container. Of note, Yufyma does have a free sharp container delivery service to your home as well as free returns.
Doesn’t sound too tricky, right? Remember, practice makes perfect.
Common Concerns
Feeling some nerves approach as the injection day circles on your calendar? It’s totally okay.
What About Side Effects?
Yuflyma, like any medication, can come with side effects, including:
Injection site reactions
Upper respiratory infections
Headaches
Rash
For a complete list, always refer to the medication guide provided with your prescription as well as your doctor.
Tips and Tricks for Successful Home Injections
Consistency is Key: Stick to a routine. Consistent timing can help make self-injections second nature.
Record Keeping: Keep a diary of your injection sites. This helps in rotating sites and tracking your condition.
Support System: Get your family or friends involved. A support system can offer a helping hand or emotional backing.
In Conclusion: Empower Yourself
Learning how to inject Yuflyma at home is a commitment to your well-being and health autonomy. Even though administering your injection might feel overwhelming at first, with each little push of the plunger, you’ll become more adept and confident in your ability to manage your treatment.
Call to Action: Take the First Step
Every journey begins with a single step — your health journey is no different. If you’ve been prescribed Yuflyma, start by discussing your treatment plan in-depth with your healthcare provider. Once you’re ready, gather your courage (and your supplies!) and take charge of your health, one injection at a time.
Medical Disclaimer
This information is offered to educate the general public. The information posted on this website does not replace professional medical advice but for general information purposes only. There is no Doctor – Patient relationship established. We strongly advised you to speak with your medical professional if you have questions concerning your symptoms, diagnosis, and treatment.
Injecting medication at home can seem daunting, but it doesn’t have to be. If your doctor has prescribed Hyrimoz for your condition, such as rheumatoid arthritis, psoriasis, uveitis or Crohn’s disease, this comprehensive guide on how to inject Hyrimoz at home will walk you through every step with clarity and confidence.
What is Hyrimoz?
Hyrimoz® (adalimumab-adaz), which you may be preparing to administer, is not just a standard therapeutic agent; it is, in fact, a biosimilar medication. As a biosimilar, it is highly similar to an existing biological medication, known as the ‘reference product’, which in this case is adalimumab, marketed under the brand name Humira®. Extensive comparison through analytical studies has shown that Hyrimoz matches its reference in terms of potency, safety, and efficacy.
Despite the similarities, it is important to note that biosimilars are not labeled as “generic” versions of biologic medications because biologics are derived from living cells and are inherently complex, and it is impossible to create an exact copy. Rest assured, before approval, Hyrimoz has gone through rigorous regulatory pathways to confirm that it is as safe and efficacious as the original biologic.
Preparing for Your First Self-Injection
Excited? Maybe a little nervous? Totally normal feelings when you’re about to take charge of your health in a hands-on way.
How to Inject Hyrimoz at Home – Starting Steps
Clean Workspace: First thing’s first—find yourself a clean, well-lit area to prepare.
Hand Hygiene: Wash your hands with soap and water. It’s simple, but it’s one of the most effective ways to prevent infection.
Gather Supplies: Get your Hyrimoz pre-filled syringe or pen, alcohol wipes, cotton balls, and a sharps container for disposal.
Storage Savvy: Remember, Hyrimoz should be stored in the refrigerator. If it’s too cold to the touch, let it sit out for 30 minutes to reach room temperature. Never use a microwave or hot water to warm it.
Step-by-Step Injection Guide
Here’s the meat and potatoes of what you came for—how to inject Hyrimoz at home:
Check It: Inspect your Hyrimoz. It should be clear, and colorless to slightly yellow. If it’s cloudy or has particles, don’t use it.
Skin Selection: Choose your injection spot—either the front of your thighs or your belly, avoiding the waistline and staying two inches clear of the navel.
Clean Up: Swipe the selected area with an alcohol wipe and let it air dry.
Get Grip-Ready: Hold the pen firmly. Remove the needle cover when you’re set to go.
Pinch an Inch: With your free hand, gently pinch the skin around the injection site.
Needle in, Steady: Press the pen firmed onto your pinched skin at 90-degree angle.
Plunge with Confidence: Press the plunger down and steadily until all the medication is injected. It typically take 10 to 15 seconds.
Release and Withdraw: Let go of your skin. Pull the needle out while keeping it at the same angle it went in.
Praise and Press: Give yourself a little internal high-five for a job well done. Place a cotton ball over the site and apply pressure for a bit. If there’s bleeding, that’s okay. Just keep the pressure on a little longer.
Sensible Disposal: Don’t recap the needle. Pop it straight into the sharps container. Of note, Hyrimoz does have a free sharp container delivery service to your home as well as free returns.
Doesn’t sound too tricky, right? Remember, practice makes perfect.
Common Concerns
Feeling some nerves approach as the injection day circles on your calendar? It’s totally okay.
What About Side Effects?
Hyrimoz, like any medication, can come with side effects, including:
Injection site reactions
Upper respiratory infections
Headaches
Rash
For a complete list, always refer to the medication guide provided with your prescription as well as your doctor.
Tips and Tricks for Successful Home Injections
Consistency is Key: Stick to a routine. Consistent timing can help make self-injections second nature.
Record Keeping: Keep a diary of your injection sites. This helps in rotating sites and tracking your condition.
Support System: Get your family or friends involved. A support system can offer a helping hand or emotional backing.
In Conclusion: Empower Yourself
Learning how to inject Hyrimoz at home is a commitment to your well-being and health autonomy. Even though administering your injection might feel overwhelming at first, with each little push of the plunger, you’ll become more adept and confident in your ability to manage your treatment.
Call to Action: Take the First Step
Every journey begins with a single step — your health journey is no different. If you’ve been prescribed Hyrimoz, start by discussing your treatment plan in-depth with your healthcare provider. Once you’re ready, gather your courage (and your supplies!) and take charge of your health, one injection at a time.
Medical Disclaimer
This information is offered to educate the general public. The information posted on this website does not replace professional medical advice but for general information purposes only. There is no Doctor – Patient relationship established. We strongly advised you to speak with your medical professional if you have questions concerning your symptoms, diagnosis, and treatment.
Psoriatic arthritis is a type of inflammatory arthritis that occurs in people with psoriasis, an autoimmune condition affecting the skin. It causes swelling, stiffness and pain in the joints as well as nail changes and overall fatigue.
Psoriatic arthritis can be difficult to diagnose in its early stages but it’s important to identify and treat it quickly. Early treatment helps relieve symptoms, improve quality of life, and potentially slow down the progression of joint damage that can occur if the disease advances untreated.
Joint Pain
One of the most common early symptoms of psoriatic arthritis is persistent joint pain, swelling, and stiffness (Mayo Clinic). This pain often affects the large joints like the knees, ankles, elbows, and wrists, but can also impact smaller joints like those in the hands and feet.
The joint pain of psoriatic arthritis tends to be asymmetric, meaning it occurs on just one side of the body rather than symmetrically on both sides. The pain and stiffness tend to be worse when joints are at rest, and improves with movement. Psoriatic arthritis joint pain may also alternate between periods of flare ups and remission.
It’s important to note that psoriatic arthritis joint pain can occur even in people who do not have skin psoriasis. The joint symptoms may precede the skin lesions in some cases. Persistent joint pain, swelling, and stiffness, especially when asymmetric and alternating between flares and remission, can be an early sign of psoriatic arthritis.
Fatigue
Fatigue is a very common symptom of psoriatic arthritis, with studies showing that up to 80% of people with PsA experience some degree of fatigue (SOURCE). The chronic inflammation associated with PsA can contribute to feelings of tiredness and lack of energy (SOURCE). This type of fatigue is different than normal tiredness after a long day – it is often described as an overwhelming, debilitating exhaustion that affects your ability to perform daily activities.
Psoriatic arthritis fatigue can range from mild to severe. You may feel generally run down or constantly drained. Simple tasks like grocery shopping, cleaning or caring for your family may wipe you out. This fatigue can be mentally exhausting as well, making it hard to concentrate or be productive. Unlike normal tiredness which gets better with rest, psoriatic arthritis fatigue may persist even when you get adequate sleep.
If you are experiencing new, unexplained and persistent fatigue along with other psoriatic disease symptoms like joint pain, stiffness or skin changes, be sure to contact your doctor. Finding the right treatment can help manage inflammation and greatly improve psoriatic arthritis fatigue.
Joint Redness and Warmth
One early symptom that should prompt suspicion of psoriatic arthritis is redness and warmth over the joints, especially when it is confined to one side of the body. Unlike regular aches and pains, the joints affected by psoriatic arthritis often become noticeably red and feel warm to the touch. This occurs when the immune system mistakenly attacks the joints, causing inflammation. According to the Mayo Clinic [“results”][0][“url”]}>, this redness and warmth is a hallmark feature of inflammatory types arthritis like psoriatic arthritis.
Some people first notice the redness and warmth before feeling any arthritic pain or stiffness. The joints most likely to develop redness and warmth are those in the hands, wrists, elbows, knees, ankles and feet. If you notice persistent redness and warmth in these joints, particularly if it is asymmetric and predominately affecting one side, be sure to point this symptom out to your doctor during your appointment. Redness and warmth in your joints in combination with other psoriatic symptoms should prompt referral to a rheumatologist for further evaluation for psoriatic arthritis.
Swollen Fingers/Toes
One early sign of psoriatic arthritis is dactylitis, also known as “sausage digit.” This refers to swelling in the fingers or toes that causes them to appear sausage-like. Dactylitis is caused by inflammation of the tendons and soft tissues of the digits. According to the National Psoriasis Foundation, dactylitis affects roughly 40-50% of people with psoriatic arthritis[1]. It often presents before any joint damage is apparent.
Dactylitis most commonly affects the middle joint of the fingers or toes, though it can occur in the wrist, ankles, and feet as well. The swelling and inflammation is often asymmetric, meaning it appears on just one finger or toe at a time, rather than symmetrically on both sides. Dactylitis causes stiffness, pain, and limited mobility in the affected digits. If you notice sausage-like swelling in your fingers or toes, it is important to see a doctor promptly, as it may be an early red flag for psoriatic arthritis[2].
Nail Changes
Nail changes are a common early sign of psoriatic arthritis. The most frequent nail manifestations are pitting, grooves, and detachment of the nail from the nail bed (onycholysis).
Pitting appears as small depressions or holes in the nail surface and gives the nail a spotted look. These pits are caused by defects in nail growth. Pitting occurs in up to 50% of those with psoriatic arthritis[1].
Nail grooves are furrows or channels that run vertically down the nail. They may be deep or superficial lines. Grooves are present in around 25% of psoriatic arthritis patients[2].
Onycholysis refers to separation of the nail from the nail bed. The nail becomes detached from the skin underneath. This occurs when inflammation damages the nail matrix. Onycholysis is seen in approximately 10-15% of those with psoriatic arthritis[3].
Getting early treatment for psoriatic arthritis can help prevent permanent nail deformities. See a doctor if nail changes accompany joint pains.
Lower Back Pain
Lower back pain is a common symptom of psoriatic arthritis. About 30-50% of people with psoriatic arthritis will experience pain and stiffness in their lower back caused by inflammation of the joints in the spine 1. This is known as axial arthritis or spondylitis. The lower back is commonly affected before other areas of the spine.
Lower back pain from psoriatic arthritis often comes on slowly and worsens over time. It can range from mild to severe. The pain and stiffness tend to be worse in the morning and improve with movement and activity. However, prolonged sitting or standing can also aggravate the pain. Lower back pain from psoriatic arthritis may switch between sides or stay on one side consistently.
If you have lower back pain along with other symptoms of psoriatic arthritis like joint swelling and skin changes, be sure to see a rheumatologist. Getting an early and accurate diagnosis is key to preventing permanent spinal joint damage. Treatment for psoriatic spondylitis aims to relieve pain, improve function, and slow the progression of the disease.
Signs you may be at risk for psoriatic arthritis
If you experience any symptoms of psoriatic arthritis, it’s important to schedule an appointment with your doctor to get an evaluation. The earlier psoriatic arthritis is diagnosed, the better the outcome with treatment. You should see a doctor if you have:
Joint pain, swelling, or stiffness that persists for more than 2 weeks (https://www.mayoclinic.org/diseases-conditions/psoriatic-arthritis/symptoms-causes/syc-20354076)
Redness or warmth over joints
Swollen fingers or toes that look like sausages
Morning joint stiffness lasting over 30 minutes
New pitting, ridges, or separation of the nails (https://www.healthline.com/health/psoriatic-arthritis-early-signs)
Fatigue that is not relieved by rest
Lower back pain, especially with joints affected elsewhere
Don’t dismiss unexplained joint pain or wait and see if it goes away. The sooner psoriatic arthritis can be diagnosed, the better the outcome with early treatment to relieve symptoms and slow disease progression. See a doctor right away if you have psoriasis and develop any joint pain or swelling.
Medical Disclaimer
The information in this video is not intended nor implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a consultation with your own doctor/health professional
Skyrizi (risankizumab-rzaa) is an injectable prescription medication used to treat certain chronic inflammatory conditions, including moderate-to-severe plaque psoriasis, active psoriatic arthritis, and moderately to severely active Crohn’s disease in adults (FDA Label).
Skyrizi works by selectively blocking IL-23, a naturally occurring protein in the body that drives inflammatory responses. By inhibiting IL-23, Skyrizi helps reduce inflammation that contributes to symptoms of the conditions it treats.
For plaque psoriasis, Skyrizi helps treat adults with moderate-to-severe symptoms involving large portions of the body or face/hands that have not responded adequately to other treatments or phototherapy. For psoriatic arthritis, Skyrizi can reduce signs/symptoms of active arthritis and improve physical function in adults with active disease. Lastly, for Crohn’s disease, Skyrizi is used to achieve and maintain clinical remission in patients who have not responded well enough to conventional Crohn’s disease therapies or have lost their response to other biologic treatments.
How Skyrizi Works
Skyrizi is a biologic medicine that works by targeting a specific protein called interleukin-23 (IL-23), which contributes to the development of inflammatory diseases like psoriasis, psoriatic arthritis, and Crohn’s disease. Skyrizi is designed to prevent IL-23 from binding to its receptor on the surface of immune cells, disrupting the inflammatory pathway that can lead to symptoms of these diseases 1.
Skryizi contains a substance called risankizumab, which attaches to the p19 part of IL-23, stopping it from activating the immune system. By doing this, Skryizi decreases inflammation and the number of certain immune cells, which can help with psoriasis, psoriatic arthritis, and Crohn’s symptoms.
In clinical trials, Skyrizi demonstrated the ability to significantly clear skin and improve symptoms in patients with moderate to severe plaque psoriasis. Reductions in disease activity have also been observed in studies of psoriatic arthritis and Crohn’s disease. Overall, by neutralizing IL-23, Skyrizi helps restore balanced immune system function and reduce harmful inflammation.
Before the Injection
Before administering a Skyrizi injection at home, it’s important to choose an appropriate injection site, gather and prepare all necessary supplies, and follow proper hygiene practices. It’s also important to make sure the medication isn’t expired and that it looks clear, not cloudy.
Recommended injection sites for Skyrizi include the front of the thighs, the abdomen, and the back of the upper arms. Avoid injecting within 2 inches of the navel or any scars or stretch marks. Rotate injection sites each time to avoid skin reactions.1
Gather all supplies needed for the injection including alcohol wipes, cotton balls, the Skyrizi injector pen and sharps container. Allow the Skyrizi pen to come to room temperature for 30 minutes before injecting. Make sure to wash your hands thoroughly with soap and water.
Before injecting, wipe the chosen site with an alcohol wipe and allow it to dry fully to sanitize the skin. Do not touch the site again before inserting the needle. Having everything prepared ahead of time helps ensure proper hygiene.2
Step-by-Step Injection
The following are the step-by-step instructions for injecting Skyrizi at home:
Remove the Skyrizi pen from the refrigerator and allow it to reach room temperature for 30 minutes before injecting. Cold Skyrizi can be more painful to inject.
Wash your hands with soap and water and assemble the injection components on a clean surface. You will need the Skyrizi pen, alcohol wipes, a cotton ball or gauze, and a sharps disposal container.
Hold the Skyrizi pen with the orange cap pointing down. Gently rock the pen back and forth 5 times. DO NOT shake the pen as this can damage the medicine. Inspect the medicine in the pen to make sure it is evenly distributed and not cloudy or discolored before injecting [1].
Remove the orange cap from the pen. The medicine should look clear to slightly yellow. Do not inject if the medicine appears cloudy, discolored, or contains large particles.
Attach the needle by securely twisting it onto the pen. Pull off the needle cap but do not throw it away yet.
Use an alcohol wipe to sanitize the injection site, either your abdomen, thighs, or upper arms. Allow the skin to air dry.
Using your thumb and forefinger, gently pinch at least 1 inch of skin around the injection site. Hold firmly.
With your other hand, insert the needle into the pinched skin at a 90 degree angle using a quick dart-like motion. Skyrizi is injected just under the skin, not into the muscle.
After the needle is fully inserted, release the pinched skin. With your thumb, slowly press the green activation button until you hear a click. Hold in place and count slowly for 5-10 seconds to deliver the full dose.
Be sure to follow the instructions included with your Skyrizi pen. A nurse or doctor can also demonstrate proper injection technique.
After the Injection
After injecting Skyrizi, it’s important to follow proper aftercare procedures at the injection site.
First, apply firm pressure to the injection site with a cotton ball or gauze for 10-15 seconds after removing the needle. This helps prevent bruising or bleeding.
The injection site may be slightly red, swollen, itchy, or bruised after injection. This is fairly common and should go away within a few days. Call your doctor if the reaction increases in severity over time (see https://www.skyrizi.com/skyrizi-complete/side-effects).
Some patients experience side effects like headache, joint pain, tiredness, or redness/rash after starting Skyrizi. These are usually mild and tend to resolve within a week or two as your body adjusts. Taking an over-the-counter pain reliever can help manage discomfort. Let your doctor know if any side effects concern you or don’t go away.
With proper aftercare and monitoring, Skyrizi injections at home can be simple and comfortable. Reach out to your healthcare provider if you have any persistent or worsening reactions so they can provide guidance and support.
Tips for Painless Injections
There are several techniques you can use to make your Skyrizi injections as comfortable and painless as possible:
Apply an ice pack or cold compress to the injection site for 5-10 minutes beforehand. This will numb the area so you feel less pain. You can also use an over-the-counter numbing cream or gel, like lidocaine, and apply it 30-60 minutes before injecting.
Stay relaxed during the injection process. Take slow, deep breaths and try to clear your mind. Tensing up can make the injection feel worse.
Distract yourself while injecting by watching TV, listening to music, or talking to someone. Focus your attention elsewhere instead of on the injection.
Rotate injection sites each time you administer Skyrizi. Switch between your stomach, thighs, and upper arms to give one area a break before injecting it again.
By using these simple tips, you can make your Skyrizi injections significantly more comfortable. The goal is to relax both your body and mind as much as possible during the process. With practice, self-injecting will become second nature and much less intimidating.
Skyrizi should be stored in the refrigerator between 2°C to 8°C (36°F to 46°F) in the original carton to protect it from light until ready to use. Do not freeze Skyrizi. Do not shake the prefilled syringe or pen. If needed, the medicine can be kept at room temperature up to 30°C (86°F) for a maximum of 30 days in the original carton to protect from light. Throw away Skyrizi if it has been out of the refrigerator for more than 30 days.
If you have any questions about using Skyrizi, contact your healthcare provider. You can also call the manufacturer’s support line at 1-866-4Skyrizi (1-866-475-9742) or visit the Skyrizi website at www.skyrizi.com for additional resources and assistance.
Conclusion
Self-administering Skyrizi injections properly at home is crucial for receiving the full benefits of this medication. When injected correctly following the steps outlined above, Skyrizi can help control inflammation and symptoms of conditions like psoriasis, psoriatic arthritis, and Crohn’s disease. Many patients find Skyrizi helps them achieve clear skin, improved joint mobility, and even remission of Crohn’s disease. By learning to inject Skyrizi comfortably at home on your own schedule, you can take control of managing your condition while avoiding unnecessary trips to the doctor’s office. With some practice and patience, most patients are able to master self-injecting this medication in a safe and effective way. Remember to follow the instructions carefully and don’t hesitate to ask your healthcare provider questions. Proper self-injection technique will help ensure you get the most out of Skyrizi’s benefits.
Additional Resources
Here are some helpful resources with further information and assistance for those taking Skyrizi:
Skyrizi Complete offers comprehensive personalized support, including injection training and financial assistance. Patients can call 1-877-266-7538 to speak with an Access Specialist.
The Patient & Practice Resources page for gastroenterology has educational materials, FAQs, and injection guides that may be helpful references.
Medical Disclaimer
This information is offered to educate the general public. The information posted on this website does not replace professional medical advice, but for general information purposes only. There is no Doctor – Patient relationship established. We strongly advised you to speak with your medical professional if you have questions concerning your symptoms, diagnosis and treatment.
Enbrel is a prescription biologic medication used to treat certain autoimmune diseases like rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, and plaque psoriasis. It comes as an autoinjector called Enbrel Sureclick, a syringe, and delivered with a machine (i.e., Enbrel Mini).
It contains the active ingredient etanercept, which is a tumor necrosis factor (TNF) blocker that targets overactive immune system cells to reduce inflammation and manage disease symptoms. Enbrel works by binding to TNF and blocking its function, which interrupts the inflammatory cascade that leads to joint swelling, pain, and damage in inflammatory forms of arthritis.
Enbrel comes in an autoinjector pen called the Enbrel SureClick that allows patients to self-administer the medication subcutaneously. The autoinjector contains a pre-filled cartridge with a single dose of Enbrel and spring-activated needle for injection. Using the autoinjector allows for a simple, convenient way to take the medication at home.
Understanding the Enbrel SureClick Autoinjector
The Enbrel SureClick autoinjector is a prefilled, single-dose disposable device designed to make self-injection straightforward and convenient. Here are the main parts to understand:
Cap – Covers the needle before injection to keep it sterile. Remove the cap just before injecting.
Viewing window – Allows you to see the Enbrel solution inside the device. Make sure the liquid looks clear to slightly yellowish and does not contain particles.
Expiration date – Check that the date has not passed before using. Do not use if expired.
Medicine – Each SureClick contains 50 mg of Enbrel in a prefilled syringe. No reconstitution is required.
Needle guard – Covers the needle after injection to prevent injury. The needle guard will deploy and lock automatically after the full dose is given.
Start button – Pressing this blue button starts the injection after the autoinjector is positioned on skin.
Injection complete indicator – Orange part that is visible when injection is done.
Familiarize yourself with these parts before using the Enbrel SureClick to ensure proper administration. With some preparation and by following all instructions, the autoinjector allows you to easily and comfortably deliver your Enbrel dose subcutaneously.
Before the Injection
Before injecting Enbrel, take the autoinjector out of the refrigerator and allow it to reach room temperature. This is an important step, as injecting cold medication can be uncomfortable. Leaving Enbrel at room temperature for about 30 minutes before injection allows the medication to warm up.
Some tips for allowing Enbrel to reach room temperature:
Take Enbrel out of the refrigerator about 30 minutes before your scheduled injection time.
Do not try to warm the medication by heating it in a microwave or placing it in hot water, as this can damage the medication.
Lay the autoinjector on a flat surface like a tabletop or counter while you wait for it to warm up.
Avoid leaving Enbrel out of the refrigerator for longer than 30 minutes before injecting. The medication can be safely kept at room temperature for up to 30 days if needed, but it’s best to inject it as soon as it reaches room temperature. You also should not put it back in the refrigerator.
Check the solution in the autoinjector window periodically. When ready to inject, the solution should be clear and colorless, with no lumps or particles.
Allowing Enbrel to warm to room temperature helps make the injection process smooth and comfortable. Once the medication has reached room temperature, you are ready for the next steps of preparing the injection site and injecting Enbrel.
Choosing the Injection Site
The recommended injection sites for Enbrel SureClick are the abdomen, thighs, and upper arms. These areas generally have more padding between the skin and muscle which makes injections easier and more comfortable.
When choosing a site, avoid injecting within 2 inches of the navel or any scar tissue or bruises. Also avoid areas that are tender, red, hard or have psoriasis plaques.
Rotate injection sites with each use. Do not inject into the exact same spot each time. Recommended rotation patterns include:
Abdomen: Divide the abdomen into quadrants using the navel as the center. Inject in a different quadrant each time.
Thighs: Alternate between left and right thigh.
Upper arms: Alternate between left and right upper arm.
Properly rotating sites allows one area to fully heal between injections. This helps minimize skin reactions or buildup of scar tissue.
Preparing the Injection Site
Before administering your Enbrel injection, you will need to properly prepare the injection site. This helps ensure the medication is delivered safely and effectively.
The first step in preparing the injection site is to wash your hands thoroughly with soap and warm water. Be sure to scrub for at least 20 seconds. This helps remove dirt and bacteria from your hands before handling the injection components.
Once your hands are clean, use an alcohol wipe to clean the skin at the injection site you have chosen. Be sure to let the alcohol fully dry before proceeding. Cleaning the skin with an alcohol wipe kills bacteria on the surface of the skin and prevents infection.
Only inject Enbrel into areas with no signs of skin problems like redness, swelling, scarring, or irritation. Avoid injecting into areas that are bruised, scarred, or feel hard. Also do not inject into moles, scars, bruises, or areas where the skin is tender, damaged, red, or hard.
Properly cleaning the injection site with an alcohol wipe before each use of Enbrel helps minimize skin reactions and ensure proper delivery of the medication.
Removing the Cap
To remove the cap from the Enbrel SureClick autoinjector, first inspect the cap to make sure it is intact and has not been previously removed. Grasp the cap and gently pull it straight off the autoinjector. Do not twist or bend the cap, as this could damage the internal needle.
Once you have removed the cap, set it aside on a clean surface. Be careful not to touch the exposed needle under the cap with your fingers, as this could contaminate the needle. The autoinjector is now ready for positioning and injection. Avoid removing the cap until you are ready to inject, as this helps keep the needle sterile.
If the cap is loose, damaged, or missing, do not use that autoinjector. Call your healthcare provider for a replacement. Never try to recap a used autoinjector or you may risk accidental needlestick injury.
Positioning the Autoinjector
Hold the autoinjector at a 90 degree angle against the injection site you have cleaned. You want to position it straight up and down, perpendicular to the skin, not at an angle. This allows the needle to properly insert into the skin.
Gently press the autoinjector firmly against the skin to start the injection. You will hear a click which signals the start of the injection, but continue holding it firmly in place. It is important to keep holding it securely against the skin throughout the entire injection process.
Do not try to inject at an angle as this can affect how well the medication is delivered. Keep the autoinjector straight up and down. Apply enough pressure so that it remains firmly in contact with the skin.
Starting the Injection
Once you have positioned the autoinjector against your skin at the injection site, you are ready to start the injection. To do this, you simply need to:
Firmly push the autoinjector all the way down against your skin until it stops moving. This will trigger the start button.
Listen for the click. The click signals that the injection has started and the medicine is being delivered.
Keep pushing down on the autoinjector. It is important to hold the autoinjector in place against your skin after the click for about 10 seconds to allow the full dose to be delivered.
You may hear a second click during this time – this is just an indicator that the injection is nearly complete.
After 10 seconds, you can then lift the autoinjector straight off of the injection site. The purple indicator will be visible to confirm the dose has been fully given.
Pushing the autoinjector all the way down until it stops moving is the action that starts the injection process. Keep the autoinjector firmly in place for 10 seconds after the click to allow the full dose to be properly injected.
Completing the Injection
After the loud click, continue holding the Enbrel SureClick autoinjector firmly against your skin for 10 seconds to ensure the full dose is delivered. Do not remove it sooner than 10 seconds, even if you think the injection is complete.
Holding the device in place allows time for all of the medication to be injected under the skin. If you remove it too soon, some medication may stay in the autoinjector and you will not get your full dose.
Keep holding the autoinjector firmly against the injection site for a slow count of 10 seconds. Count slowly in your head or out loud. After counting to 10, you can then lift the autoinjector straight up from your skin to complete the injection.
The blue indicator will now be visible to confirm the injection is complete. You may see a few drops of liquid on your skin, which is normal. Press a cotton ball or gauze pad over the injection site and hold for 10 seconds. Do not rub the site.
After the Injection
After you have completed the injection, you can remove the autoinjector from your skin. Check the viewing window to ensure the purple indicator is visible, confirming the full dose has been delivered. There may be a small amount of blood at the injection site – you can press a cotton ball or gauze over the injection site for 10 seconds to stop any bleeding. Do not rub the injection site.
It is important to properly dispose of the used autoinjector right away. Place the used SureClick autoinjector into an FDA-cleared sharps disposal container right away after use. Do not throw away (dispose of) loose needles and syringes in your household trash. Do not recycle your used sharps disposal container.
If you do not have an FDA-cleared sharps disposal container, you may use a household container that is:
Made of a heavy-duty plastic
Can be closed with a tight-fitting, puncture-resistant lid, without sharps being able to come out
Upright and stable during use
Leak-resistant
Properly labeled to warn of hazardous waste inside the container
When your sharps disposal container is almost full, follow your community guidelines for the right way to dispose of your sharps disposal container. There may be state or local laws about how to throw away used needles and syringes.
Medical Disclaimer
This information is offered to educate the general public. The information posted on this website does not replace professional medical advice, but for general information purposes only. There is no Doctor – Patient relationship established. We strongly advised you to speak with your medical professional if you have questions concerning your symptoms, diagnosis and treatment.
It’s been a while since I’ve posted on RheumDoctor.com but here goes! Today I’ll be demonstrating how to inject Tremfya at home. Tremfya recently received FDA approval for the treatment of psoriatic arthritis and already has approval for the treatment of plaque psorisais. It comes as a prefilled syringe as well as a pen. I’ll be demonstrating its use with a pen.
Preparing for your injection
· Keep your medication stored in the refrigerator until use
Before injecting medication, take the autoinjector or prefilled syringe out of the refrigerator.
Allow it to warm up to room temperature.
· Pick a place in your house that is clean and has room for your materials (such as the kitchen table).
· Wash your hands thoroughly with either:
Soap & water
Hand sanitizer
· Choose an area to inject – Thigh or Stomach.
Choose an area that is intact and clear.
It should not have any of the following:
Cuts
Scrapes
Bruises
Psoriasis patches
If you have extensive psoriasis, inject between patches
Moles
Scars
Please rotate area each time you inject (shown in picture below).
Cleanse chosen area
Cleanse chosen area with either of the following:
Alcohol swab
Alcohol and a cotton ball
Use the chosen alcohol material to “swipe” area
Can either use a circular motion or wipe in “strips”
Allow the area to dry
How to inject Tremfya with an autoinjector pen
Observe the medication in the window to be sure that it is clear (no cloudiness or crystals)
You will see a small air bubble within the window, this is normal and will not cause harm when injecting
· Remove the cap
· Press the tip of the auto-injector down in the skin at a 90 degree angle until it is flush with the skin
· Press button and hold for 15 seconds
· Viewing window will turn yellow, but continue to hold the button for the full 15 seconds · Lift the auto-injector straight up
Injecting Tremfya with a prefilled syringe
· Pull off the cap and observe the syringe to be sure that it is clear (no cloudiness or crystals)
· Pinch the skin around the injection site and enter at a 45-degree angle
· Press the plunger (slowly) to administer the medication
· Once the medication is fully administered, the plunger will reach the bottom and a spring will place a cover over the needle
After the injection
Properly dispose of the entire autoinjector/pen or prefilled syringe
Sharps Container
Can be purchased at your local pharmacy
Disposal
Hospitals may take full sharps containers, ask first.
Pharmacies and Doctors’ offices are not allowed to take used syringes or needle
Discard remaining materials in the trash (cap, alcohol swabs, etc.)
Injection site image: By British Columbia Institute of Technology (BCIT). Download this book for free at http://open.bccampus.ca [CC BY 4.0 (http://creativecommons.org/licenses/by/4.0)], via Wikimedia Commons
Medical Disclaimer
This information is offered to educate the general public. The information posted on this website does not replace professional medical advice, but for general information purposes only. There is no Doctor – Patient relationship established. We strongly advised you to speak with your medical professional if you have questions concerning your symptoms, diagnosis and treatment.
